MEDICINAL CHEMISTRY

Burger's Medicinal Chemistry and Drug Discovery, 6 Volume Set, 6th Edition

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This new sixth edition of Burger's Medicinal Chemistry and Drug Discovery offers several new and unique features. For the first time, an online version of this major reference work will offer updated content from the print edition and easy access. For the first time, all volumes are structured entirely according to content and published simultaneously to provide broad coverage of medicinal chemistry and drug discovery for new or experienced medicinal chemists, biologists, pharmacologists and molecular biologists. This includes a current and global perspective of drug design, and drug development.With expanded content from 69 chapters to over 100 chapters, this sixth edition of Burger's Medicinal Chemistry and Drug Discovery includes more than 50% new material. An entire section has been dedicated to cancer research. Areas included are those at the foreground of life science including:* Proteomics* Genomics* Bioinformatics* Combinatorial Chemistry* High-Throughput Screening* Blood Substitutes* Allosteric Effectors as Potential Drugs* COX Inhibitors* Statins* High-Throughput Pharmacology* and More.The new sixth edition of Burger's Medicinal Chemistry and Drug Discovery is a Memorial Edition to Professor Alfred Burger who published this major reference work in the first edition as "Medicinal Chemistry" in two volumes in 1951. Dr. Burger's research focused on analgesics, antidepressants and chemotherapeutic agents. He is one of the few academicians to have a drug, designed and synthesized in his laboratories and brought to market. Dr. Burger's contribution to the fields of medicinal chemistry and drug discovery are well renowned and documented. He received the Louis Pasteur Medal of the Pasteur Institute and the American Chemical Society Smissman Award.

Content

VOLUME 1
Structure Based Drug-Design
History of Quantitative Structure Activity Relationships
Recent and Developing Trends in QSAR: From Data Analysis and Model Validation to Drug Design and Discovery
Molecular Modeling in Drug Design
Drug-Target Binding Forces: Advances in Force Field Approaches
Combinatorial Library Design, Molecular Similarity and Diversity Applications
Virtual Screening
Docking and Scoring Functions/Virtual Screening
Bioinformatics
Chemical Information Computing Systems in Drug Discovery
X-ray Crystallography Drug Discovery
Electron Microscopy of Biological Macromolecules
Design of Peptidomimetics
Approaches to the Rational Design of Enzyme Inhibitors
Chirality and Biological Activity
Structural Concepts in the Prediction of the Toxicity of Therapeutical Agents
Natural Products as Leads for New Pharmaceuticals
Analog Design
NMR and Drug Discovery
Mass Spectrometry and Drug Design
VOLUME 2
Combinatorial Chemistry and Multiple Parallel Synthesis
Highthroughput Screening for Lead Discovery
High Throughput Pharmacology
The Application of Recombinant DNA Technology in Medicinal Chemistry and Drug Discovery
Oligonucleotide Therapeutics
Therapeutic Agents Acting on RNA
Carbohydrate Based Therapeutics
Membrane Transport Proteins and Drug Transport
Allosteric Proteins and Drug Discovery
Receptor Targets in Drug Discovery and Development
Large Scale Synthesis
Principles of Drug Metabolism
Metabolic Considerations in Prodrug Design
Retrometabolism-Based Drug Design and Targeting
Drug Discovery: The Role of Toxicology
Drug Absorption, Distribution, and Elimination
The FDA and Regulatory Issues
Intellectual Property in Drug Discovery and Biotechnology
Nicotinic Acetylcholine Receptors
Physicochemical Characterization and Principles of Oral Dosage Form Selection
VOLUME 3
Cardiac Drugs: Antianginal, Vosodilators, Antiarrhythmic
Diuretics and Uricosuric Agents
Myocardial Infarction Agents
Endogenous Vasoactive Peptides
Hematopoietic Agents
Anticoagulatns, Antithrombotics and Hemostatics
Antihyperlipedemic Agents
Oxygen Delivery via Allosteric Effectors of Hemoglobin, Blood Substitutes, and Plasma Expanders
Sickle Cell Anemia
Iron Chelators and Therapeutic Uses
Thyroid Hormones and Thyromimetics
Male Sex Hormones, Analogs, and Antogonists
Anti-inflammatory Steroids
Female Sex Hormones, Contraceptives & Fertility Drugs
Fundamentals of Steroid Chemistry and Biochemistry
VOLUME 4
Peptide and Protein Hormones, Peptide Neurotransmitters, and Therapeutic Agents
Inhibitors of Gastric Acid Secretion
Chemokines and Cytokine Modulators
COX Inhibitors and Leukotriene Modulators
Agents Acting on Prostanoid Receptors
Retinoids
Vitamins
Life Style and Over-the-Counter Agents
Radiopaques
Microarrays and Gene Expression Profiling Applied to Drug Research
SNPs: Single Nucleotide Polymorphisms and Pharmacogenomics
Gene Therapy with Plasmid DNA
Insulin and Hypoglycemic Agents
VOLUME 5
Molecular Biology of Cancer
Synthetic DNA-targeted Chemotherapeutic Agents and Related Tumor-Activated Prodrugs
Antitumor Natural Products
Radiosensitizers and Radioprotective Agents
Synthetic Anti-angiogenic Agents
Future Strategies in Immunotherapy
Selective Toxicities
Drug Resistance in Cancer Chemotherapy
Antiviral Agents, DNA
Antiviral Agents, RNA (Viruses other than HIV), Orthopoxviruses
Rationale of Design of Anti-HIV Drugs
Organ Transplantation Drugs
Synthetic Antibacterial Agents
Lactam Antibiotics
Tetracyclines, Aminolycoside, Macrolide, and Miscellaneous Antibiotics
Antimycobacterial Agents
Antifungal Agents
Antimalarial Agents
Antiprotozoal Agents
Anthelmintic Agents
VOLUME 6
Andrenergics and Andrenergic Blocking Agents
Cholinergics
Anticholinergic Drugs
CNS Stimulants
Sedatives and Hypnotics
Anticonvulsants
Analgesics
Antidepressants
Antianxiety Agents
Antipsychotic Agents
Investigative Agents for use in Neurodegenerative Conditions
Therapeutic and Diagnostic Agents for Parkinson's Disease
Alzheimer's Disease: Search for Therapeutics
Cognition Enhancers
Drugs to Treat Eating and Body Weight Disorders

Download

Vol 1 burgers medicinal chemistry.pdf
http://mihd.net/x2v7fc
Vol 2 burger textbook of medicinal chemistry.pdf
http://mihd.net/3qzpaf
Vol 3-burger medicinal chemistry.pdf
http://mihd.net/akzwnl
Vol 4-burger medicinal chemistry.pdf
http://mihd.net/xnugqw
Vol 5-burger medicinal chemistry.pdf
http://mihd.net/wy2s50

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Remington The Science and Practice of Pharmacy Twenty First Edition

Remington
The Science and Practice
of Pharmacy
Twenty First Edition




For over 100 years, Remington has been the definitive textbook and reference on the science and practice of pharmacy. This Twenty-First Edition keeps pace with recent changes in the pharmacy curriculum and professional pharmacy practice.
More than 95 new contributors and 5 new section editors provide fresh perspectives on the field. New chapters include pharmacogenomics, application of ethical principles to practice dilemmas, technology and automation, professional communication, medication errors, re-engineering pharmacy practice, management of special risk medicines, specialization in pharmacy practice, disease state management, emergency patient care, and wound care.
Purchasers of this textbook are entitled to a new, fully indexed Bonus CD-ROM, affording instant access to the full content of Remington in a convenient and portable format.
A must-have resource for all in the pharmaceutical industry!
Contents
I. Orientation

1. Scope of Pharmacy
2. Evolution of Pharmacy
3. Ethics and Professionalism
4. The Practice of Community Pharmacy
5. Pharmacists in Industry
6. Pharmacists in Government
7. Pharmacists and Public Health
8. Information Resources in Pharmacy and the Pharmaceutical Sciences
9. Clinical Drug Literature
10. Research

II. Pharmaceutics

11. Metrology and Pharmaceutical Calculations
12. Statistics
13. Molecular Structure, Properties, and States of Matter
14. Complex Formation
15. Thermodynamics
16. Solutions and Phase Equilibria
17. Ionic Solutions and Electrolytic Equilibria
18. Tonicity, Osmoticity, Osmolality, and Osmolarity
19. Chemical Kinetics
20. Interfacial Phenomena
21. Colloidal Dispersions
22. Coarse Dispersions
23. Rheology

III. Pharmaceutical Chemistry

24. Inorganic Pharmaceutical Chemistry
25. Organic Pharmaceutical Chemistry
26. Natural Products
27. Drug Nomenclature—United States Adopted Names
28. Structure-Activity Relationship and Drug Design
29. Fundamentals of Medical Radionuclides

IV. Pharmaceutical Testing, Analysis and Control

30. Analysis of Medicinals
31. Biological Testing
32. Clinical Analysis
33. Chromatography
34. Instrumental Methods of Analysis
35. Dissolution

V. Pharmaceutical Manufacturing

36. Separation
37. Powders
38. Property-Based Drug Design and Preformulation
39. Solutions, Emulsions, Suspensions and Extracts
40. Sterilization
41. Parenteral Preparations
42. Intravenous Admixtures
43. Ophthalmic Preparations
44. Medicated Topicals
45. Oral Solid Dosage Forms
46. Coating of Pharmaceutical Dosage Forms
47. Extended-Release and Targeted Drug-Delivery Systems
48. The New Drug Approval Process and Clinical Trial Design
49. Biotechnology and Drugs
50. Aerosols
51. Quality Assurance and Control
52. Stability of Pharmaceutical Products
53. Bioavailability and Bioequivalency Testing
54. Plastic Packaging Materials
55. Pharmaceutical Necessities

VI. Pharmacodynamics

56. Diseases: Manifestations and Pathophysiology
57. Drug Absorption, Action and Disposition
58. Basic Pharmacokinetics and Pharmacodynamics
59. Clinical Pharmacokinetics and Pharmacodynamics
60. Principles of Immunology
61. Adverse Drug Reactions and Clinical Toxicology
62. Pharmacogenomics
63. Pharmacokinetics/Pharmacodynamics in Drug Development

VII. Pharmaceutical and Medicinal Agents

64. Diagnostic Drugs and Reagents
65. Topical Drugs
66. Gastrointestinal and Liver Drugs
67. Blood, Fluids, Electrolytes and Hematological Drugs
68. Cardiovascular Drugs
69. Respiratory Drugs
70. Sympathomimetic Drugs
71. Cholinomimetic Drugs
72. Adrenergic Antagonists and Adrenergic Neuron Blocking Drugs
73. Antimuscarinic and Antispasmodic Drugs
74. Skeletal Muscle Relaxants
75. Diuretic Drugs
76. Uterine and Antimigraine Drugs
77. Hormones and Hormone Antagonists
78. General Anesthetics
79. Local Anesthetics
80. Antianxiety Agents and Hypnotic Drugs
81. Antiepileptic Drugs
82. Psychopharmacologic Agents
83. Analgesic, Antipyretic, and Anti-inflammatory Drugs
84. Histamine and Antihistaminic Drugs
85. Central Nervous System Stimulants
86. Antineoplastic Drugs
87. Immunoactive Drugs
88. Parasiticides
89. Immunizing Agents and Allergenic Extracts
90. Anti-Infectives
91. Enzymes
92. Nutrients and Associated Substances
93. Pesticides

VIII. Pharmacy Practice
Fundamentals of Pharmacy Administration

94. Applications of Ethical Principles to Practice Dilemmas
95. Technology and Automation
96. The Patient: Behavioral Determinants
97. Patient Communication
98. Patient Compliance
99. Drug Education
100. Professional Communications
101. The Prescription
102. Providing a Framework for Ensuring Medication Use Safety
103. Poison Control
104. Drug Interactions
105. Extemporaneous Prescription Compounding
106. Nuclear Pharmacy Practice
107. Nutrition in Pharmacy Practice
108. Pharmacoepidemiology
109. Surgical Supplies
110. Health Accessories

Social, Behavioral, andEconomic, and Administrative Sciences

111. Laws Governing Pharmacy
112. Re-engineering Pharmacy Practice
113. Pharmacoeconomics
114. Community Pharmacy Economics and Management
115. Product Recalls and Withdrawals
116. Marketing Pharmaceutical Care Services
117. Documenting, Billing, and Reimbursement for Pharmaceutical Care Services
118. Pharmaceutical Risk Management
119. Integrated Health Care Delivery Systems

Patient Care

120. Specialization in Pharmacy Practice
121. Pharmacists and Disease State Management
122. Development of a Pharmacy Care Plan and Patient Problem-Solving
123. Ambulatory Patient Care
124. Self-Care
125. Diagnostic Self-Care
126. Preventive Care
127. Hospital Pharmacy Practice
128. Emergency Medicine Pharmacy Practice
129. Long-Term Care
130. Aseptic Processing for Home Infusion Pharmaceuticals
131. The Pharmacist's Role in Substance Use Disorders
132. Complementary and Alternative Medical Health Care
133. Chronic Wound Care

Index
DOWNLOAD FROM

http://rapidshare.com/files/45552201/Remington.part1.rar

http://rapidshare.com/files/45685773/Remington.part2.rar

IMPORTANT
YOU Need The Program Diamon tool to make it work , and only this program not other mounting program
download daemon from here:
http://www.disc-tools.com/request?p=73b4c3cb2620037f6e27954683b856bd/daemon408-139-x86.exe

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1-set daemon up
2- Put Regminton on CD
3-do not set up the program regminton from cd but
4-click:"run from cd"
do not INSTALL the regminton program from CD just put regminton cd in it and it will make an autoplay itself giving you a green window with 2 choices . choose: "run from cd"





OTHER LINKS FOR REGMiNTON:
part 1 100MB
http://rapidshare.de/files/25208340/REM05PER.part1.rar.html
Part2 40MB
http://rapidshare.de/files/25208001/REM05PER.part2.rar.html
password : AboJim
OR
part1
http://www.badongo.com/file/1070295
part2
http://www.badongo.com/file/1072021

password : AboJim



Or:
Part - I: http://rapidshare.com/files/45552201/Remington.part1.rar
Part - II: http://rapidshare.com/files/45685773/Remington.part2.rar