DRUG INTERACTIONS

>> Monday, January 18, 2010

Antiepileptic Drugs: Combination Therapy and Interactions




Antiepileptic Drugs: Combination Therapy and Interactions
Pages: 514 Date: 2005 ISBN:052182219X Rared PDF File Rapidshare & Depositfiles 2 MB


This book reviews the use of antiepileptic drugs focusing on the interactions between these drugs and between antiepileptics and other drugs. These interactions can be beneficial or can cause harm. The aim of this book is to increase awareness of the possible impact of combination pharmacotherapies. Pharmacokinetic and pharmacodynamic interactions are discussed supported by clinical and experimental data. The book consists of five sections covering the general concepts and advantages of combination therapies, the principles of drug interactions, the mechanisms of interactions, drug interactions in specific populations or in patients with co-morbid health conditions, and concludes with a look at the future directions for this field of research. The book will be of interest to all who prescribe antiepileptics to epileptic and non-epileptic patients, including epileptologists, neurologists, neuro-pediatricians , psychiatrists and general practitioners.


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Drug-Induced Liver Disease .. 2 editions














Book Description:

Epidemiological studies have found that drugs are now the most common cause of liver failure in the United States, and the past decade has seen an explosion of new information concerning the immunology, toxicology, and pharmacology of drug-induced liver disease. This expertly written Second Edition supplies an in-depth discussion of the recent developments in drug-induced hepatotoxicity, covering mechanisms, histopathology, management, risk factors, and patterns of drug and toxin-induced liver disease.

# Publisher: Informa Healthcare
# Number Of Pages: 808
# Publication Date: 2007-07-10
# ISBN / ASIN: 0849398967
# EAN: 9780849398964


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Drug-Induced Liver Disease
By Neil Kaplowitz, Laurie D. DeLeve
Publisher: Informa Healthcare
Number Of Pages: 784
Publication Date: 2002-10-16
ISBN-10 / ASIN: 0824708113
ISBN-13 / EAN: 9780824708115
Binding: Hardcover

Featuring more than 4100 references, Drug-Induced Liver Disease will be an invaluable reference for gastroenterologists, hepatologists, family physicians, internists, pathologists, pharmacists, pharmacologists, and clinical toxicologists, and graduate and medical school students in these disciplines.

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Herbal Supplements-Drug Interactions: Scientific and Regulatory Perspectives








The international popularity of herbal remedies has recently outpaced quality information on the utilization and dosing of these compounds. This book fills a void in the literature by offering an authoritative overview of the mechanisms of herbal remedies and their impact on standard medications. It offers a practical approach that focuses not only on specific drug interactions, but the mechanisms behind those interactions and their clinical significance. With contributions from leading experts on the subject, this text examines the overall use of herbs, includes sections on individual herbs, and considers pertinent regulatory issues and concerns in industry.

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Stockley's Drug Interactions, Other eddition




Karen Baxter, "Stockley's Drug Interactions, 7th Edition"
Not Avail; 7 Har/Cdr edition ISBN: 0853696640 1208 pages CHM 11,4 Mb

Univ. of Nottingham Medical School, UK. Reference includes more than 13,000 references for more than 2,500 monographs. Provides international, British, and American drug names and extensive bibliographies. Covers clinical evidence, mechanism, importance, and over-the-counter and prescribed drugs. For clinicians.

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Overcoming Steroid Insensitivity in Respiratory Disease




Overcoming Steroid Insensitivity in Respiratory Disease
Publisher:Wiley Pages:304 2008-05-19 ISBN:0470058080 PDF 3.5 MB

Written by well-known experts in field, this is the first book dedicated to dealing with the single most challenging management issue in long-term steroid therapy.

Overcoming Steroid Insensitivity in Respiratory Disease reviews important new advances in therapeutics and provides the clinician with the most up to date information on one of the most significant therapeutic challenges to effective management of these diseases. This unique book is an invaluable resource for all postgraduate students and specialist physicians in pulmonology allergy and asthma. It is also of interest for workers in biomedical and pharmaceutical research.

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Litt's Drug Eruption Reference Manual Including Drug Interactions




Litt's Drug Eruption Reference Manual Including Drug Interactions, 14th Edition
Publisher:Informa HealthCare Pages:657 2008-01-31 ISBN:0415458854 PDF 3.1 MB

Litt's Drug Eruption Reference Manual, 14th edition, has been updated and improved and incorporates dermatological drug eruptions plus reactions affecting the nails, hair, nails, eyes and mucosal.. This valuable resource also includes herbal and supplements reactions, in addition to hazardous drug-drug interactions. This book is a must have for all dermatologists, general practitioners and those working in emergency medicine.



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Drugs Compromising Male Sexual Health by Walter Krause
Publisher: Springer 2008-01 | 702 Pages | ISBN: 3540698590 | PDF | 2.8 MB

This concise drug guide lists 500 substances, such as pharmaceutical drugs, lifestyle drugs, and environmental toxicants, that show documented untoward effects on the male sexual organs and their functions. All substances are listed in user-friendly alphabetical order with a uniform structure throughout the book. Each listing includes evidence-based information with up-to-date references and all studies mentioned are evaluated and categorized according to study and sample types.

This unique compendium provides more detailed information on each drug than any other standard pharmacology title. Knowledge of the relevance of undesirable drug effects will enable the physician working in the fields of andrology and reproductive medicine to decide whether there is a relationship between a disturbance of male sexual function and a drugs adverse side effects. An electronic CD-ROM accompanies the book.


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Drug-Drug Interactions, Second Edition




A. David Rodrigues “Drug-Drug Interactions, Second Edition"
Informa Healthcare 2008-02-08 ISBN: 0849375932 768 pages PDF 6,3 Mb

Helping researchers predict drug interactions in a more accurate and effective manner, this comprehensive volume covers every critical aspect of metabolism-based drug-drug interactions, including preclinical, clinical, toxicological, regulatory, and marketing perspectives by renowned thought leaders in their respective fields. Thoroughly updated, the Second Edition reflects key developments in the field, including an improved understanding of the relationship between transporters and enzymes in drug metabolism and drug interactions. Formatted to benefit the reader, this source provides helpful case examples, representative enzyme systems, and computer-aided modeling, as well as 200 valuable tables, equations, drawings, and photographs to clarify key concepts.





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Drugs and Human Lactation




Drugs and Human Lactation
Elsevier Science ISBN: 0444819819 1996-11-01 PDF 722 pages 23.6 MB

Now in its second edition, Drugs and Human Lactation is a comprehensive guide to the content and consequences of xenobiotics and micronutrients in human milk, and remains by far the most thorough and extensive work available on this subject. The excellent methodology used for the compilation of the 1st edition has been retained.

It begins with an outline of the processes by which substances enter milk during its formation, the effects of drugs on the milk production process, the main determinants of drug excretion into milk and their disposition in the child. There follows an analysis of current data on 234 individual drugs, describing the extent of their passage into human milk, and assessing the risk to the suckling infant. Vitamins and essential trace elements, and radiopharmaceuticals are similarly reviewed. Also included is an account of the factors that influence the passage of environmental and occupational chemicals into milk. The result is a complete overview of what is known and proven, with clear pointers to matters which require further study, and brings the various subject areas up to date. Risks, uncertainties and false alarms which exist have been defined in such a way that they can be avoided.
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Drug Hypersensitivity




W. j. Pichler “Drug Hypersensitivity"
Not Avail 2007-05-31 ISBN: 3805582692 438 pages PDF 6,4 Mb


Drug hypersensitivities are immune-mediated reactions characterized by exanthems, fever and internal organ involvement. They represent a challenging field of research: many different drugs can induce a variety of clinical symptoms through multiple mechanisms of drug-host interaction, many of which are poorly understood. This is the first book to approach the phenomenon of drug hypersensitivity in a comprehensive manner. Besides epidemiological aspects, it addresses the immunological mechanisms underlying these complicated reactions which go far beyond the IgE-mediated drug allergies also considered in the book. Furthermore, the book covers clinical manifestations and new diagnostic methods, and introduces some recently established animal models. Well-accepted and also completely new concepts are presented and discussed in detail. Many topics are treated from multiple perspectives, and the 33 chapters are thoroughly cross-referenced. This publication will be of immense value not only to allergologists, dermatologists and anyone prescribing medication, but also to scientists in a pharmaceutical industry challenged by the economic effects of failures in drug development or drug removal from the market. Elucidating the mechanisms of drug hypersensitivity will not only help to identify patients at risk but will also provide novel insights into the pathophysiology of numerous immune-mediated diseases.



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Stockley's Drug Interactions, 7th Edition






Title: Stockley's Drug Interactions, 7th Edition (Drug Interactions (Stockley))
Author: Ivan H Stockley
Publisher: Not Avail
Publication Date: 2005-10-30
Number Of Pages: 1208
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Drug-Drug Interaction Primer: A Compendium of Case Vignettes for the Practicing Clinician




Drug-Drug Interaction Primer: A Compendium of Case Vignettes for the Practicing Clinician
American Psychiatric Publishing 2007-06-05 ISBN: 1585623059 408 pages PDF 13,5 MB

This user-friendly resource offers complete and comprehensive coverage of the difficult challenges posed by drug-drug interactions. Over 170 case vignettes illustrate a variety of interactions (DDIs) to provide an unintimidating even entertaining approach to understanding these issues. Drug-Drug Interaction Primer builds on the author's earlier work, Drug Interactions Casebook: The Cytochrome P450 System and Beyond, and features updated references throughout and 29 new cases that provide such clinical examples as: a patient diagnosed with schizoaffective disorder transitions from haloperidol to aripiprazole with disastrous results; an AIDS patient's trimethoprim-sulfamethoxazole is replaced with warfarin following atrial fibrillation, resulting in ischemic stroke; and a delusional patient on risperidone is placed on phenytoin following seizures, and delusions return.

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Drug-Induced Mitochondrial Dysfunction




Drug-Induced Mitochondrial Dysfunction (US$145)
Stationary Office Pages: 616 2008-09-22 ISBN:0470111313 9 MB Rapidshare and Megaupload

Drug-Induced Mitochondrial Dysfunction
By James A. Dykens, Yvonne Will

* Publisher: Wiley-Interscience
* Number Of Pages: 616
* Publication Date: 2008-09-22
* ISBN-10 / ASIN: 0470111313
* ISBN-13 / EAN: 9780470111314
* Binding: Hardcover

Product Description:

This is the definitive, one-stop resource on preclinical drug evaluation for potential mitochondrial toxicity, addressing the issue upfront in the drug development process. It discusses mitochondrial impairment to organs, skeletal muscle, and nervous systems and details methodologies used to assess mitochondria function. It covers both in vitro and in vivo methods for analysis and includes the latest models. This is the authoritative reference on drug-induced mitochondrial dysfunction for safety assessment professionals in the pharmaceutical industry and for pharmacologists and toxicologists in both drug and environmental health sciences.


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Drug-DNA Interactions: Structures and Spectra (2008)



Drug-DNA Interactions: Structures and SpectraPublisher: Wiley English ISBN: 0471786268 370 pages 2008 PDF 16 Mb
Description:
Learn vital information about drug-DNA interactions from Drug-DNA Interactions: Structures and Spectra, the only comprehensive book written about this topic. Understand the types of structural and bonding information that can be obtained using specific physico-chemical methods and discover how to design new drugs that are more effective than current treatments and have fewer side effects. Find detailed information about X-ray crystallography, NMR spectroscopy, molecular modeling, and optical spectroscopy such as UV-Visible absorption, fluorescence, circular dichroism (CD), flow linear dichroism (FLD), infrared (IR) and Raman spectroscopy.
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Drugs and the Liver: A Guide to Drug Handling in Liver Dysfunction



Publisher:Pharmaceutical Press Pages:324 2008-01-31 ISBN:0853697108 PDF 1 MB
Liver disease is a widespread and increasing problem throughout the world, however little is published on how different types and degrees of liver dysfunction affect the body's ability to handle medicines."Drugs and the Liver" is designed to assist practitioners in making pragmatic choices for their patients. It aims to: enable the practitioner to assess liver function using biochemical markers, other tests, signs, symptoms and disease knowledge; identify which pharmacokinetic and pharmacodynamic parameters of a drug are likely to be affected by different types of liver disease; and consider the impact of a drug's side effects on a patient with liver disease.This practical guide covers background information on liver function, the principles of drug use in liver disease and includes a section of worked examples of commonly asked questions. It will be invaluable to clinical pharmacists and anyone making medicine choices in patients with liver impairment.

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Handbook of Food-Drug Interactions





Beverly J. McCabe “Handbook of Food-Drug Interactions" CRC 2003 ISBN: 084931531X 567 pages PDF 3,5 MB
While pharmacists may know that a particular drug is inactive in a given pH environment, they may not know the pH of common foods. For dietitians the situation is reverse. With contributions from pharmacy, dietetics, and medicine, this book serves as a guide to the interdisciplinary prevention or correction of negative food-drug interactions. While other books simply list potential food-drug interactions, this book gives specific recommendations based on frequency and severity of reactions. It provides special dietary modifications necessary for prevention of adverse side effects. It also identifies new foods, supplements, and ethnic dishes that may contribute significantly to food-drug interactions.

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Drug Benefits and Risks: International Textbook of Clinical Pharmacology




Publisher:IOS Press Pages:821 2008-07-31 ISBN:158603880X PDF 4.8 MBThis is an inclusive reference exploring the scientific basis and practice of drug therapy. The key concept is to look at the balance between the benefits and risks of drugs but in this context also the social impact which drugs have in modern societies is highlighted. Taking an evidence-based approach to the problem, the practice of clinical pharmacology and pharmacotherapy in the developing as well as the developed world is examined. For this purpose the book* Covers general clinical pharmacology, pharmacology of various drug groups and the treatments specific to various diseases* Gives guidance on how doctors should act so that drugs can be used effectively and safely* Encourages the rational use of drugs in societyThis book brings together a large amount of excellent content that will be invaluable for anyone working within, or associated with, the field of clinical pharmacology and pharmacotherapy - undergraduates, postgraduates, regulatory authorities and the pharmaceutical industry.

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