BIONANOTECHNOLOGY

>> Monday, January 18, 2010

BioNanotechnology 2007




BioNanotechnology by Elizabeth Papazoglou
Morgan and Claypool Publishers ISBN 1598291386 2007-08-21 PDF 139 Pages 4.6 MB

This book aims to provide vital information about the growing field of bionanotechnology for undergraduate and graduate students, as well as working professionals in various fields. The fundamentals of nanotechnology are covered along with several specific bionanotechnology applications, including nanobioimaging and drug delivery which is a growing $100 billions industry. The uniqueness of the field has been brought out with unparalleled lucidity; a balance between important insight into the synthetic methods of preparing stable nano-structures and medical applications driven focus educates and informs the reader on the impact of this emerging field. Critical examination of potential threats followed by a current global outlook completes the discussion. In short, the book takes you through a journey from fundamentals to frontiers of bionanotechnology so that you can understand and make informed decisions on the impact of bionano on your career and business.

CONTENTS

Introduction
0.1 Bionanotechnology: A Historical Perspective
0.2 Nanotechnology and Bionanotechnology
0.3 Notable Nanoimages in Bionanotechnology
0.3.1 AFM-Qd
0.3.2 Nano-drug Delivery Chip
0.3.3 Atomic Force Microscopy Image (AFM) of SWNT
0.3.4 Scanning Electron Microscopy Image (SEM) of SWNT
0.4 Opportunities and Challenges of Bionanotechnology
0.5 Growth potential of Nanotechnology and Related Expenditures
References

1. The Significance of Nano Domain
1.1 Limitations of Micron Size
1.2 Need for Nano-Size—Surface Volume Ratio Significance
1.3 Significance and Key Features of Nano-Size
1.4 Derivation of Bohr’s Atomic Radius of a Hydrogen Atom
1.5 Comparison of Particle Behavior at Nano-Size to Macro Size: Gold and Titania
1.6 Advantages of Scaling Down—Nano-Size
References

2. Nano Drug Delivery
2.1 Conventional Drug Delivery
2.1.1 First Pass Effect
2.1.2 Routes of Delivery
2.2 Targeted Drug Delivery
2.3 Chemistry of Drug Delivery Vehicles
2.3.1 Nanocapsules
2.3.2 Unilamellar Liposomal Vesicles
2.3.3 Nanoparticles
2.3.4 Microemulsions
2.4 Delivery Profiles
2.4.1 Rate-Preprogrammed Drug Delivery Systems
2.4.2 Activation-Modulated Drug Delivery Systems
2.4.3 Feedback-Regulated Drug Delivery Systems
2.4.4 Site-Targeting Drug Delivery Systems
2.5 The Role of Nanotechnology in Drug Delivery
2.5.1 Transdermal
2.5.2 Blood Brain Barrier
2.6 Advantages of Targeted Drug Delivery Systems
References

3. BioNanoimaging
3.1 Quantum Dots
3.2 Ultrasound Contrast Agents
3.3 Magnetic Nanoparticles
References

4. Successful Applications of Bionanotechnology
4.1 Nanostructures and Nanosystems
4.1.1 Nanopore Technology
4.1.2 Nano Self-Assembling Systems
4.1.3 Cantilevers
4.1.4 Nanoarrays
4.2 Nanoparticles
4.2.1 Quantum Dots (QDs)
4.2.2 Paramagnetic Iron Oxide Crystals
4.2.3 Dendrimers
4.2.4 Carbon Nanotubes
4.2.5 Nanosomes and Polymersomes
4.3 In Vitro Diagnostics
4.4 Medical Application of Nanosystems and Nanoparticles
4.4.1 Drug Delivery Applications
4.4.2 Nanoparticles in Molecular Imaging
4.5 Summary and Conclusions
References

5. Synthesis of Gold, Titania, and Zinc Oxide
5.1 Synthesis of Gold
5.1.1 Background
5.1.2 Brust Method of Synthesis of Thiol Derivatized Gold NPs by Biphasic Reduction
5.1.3 Gold Colloids
5.1.4 Gold Nanofilm
5.1.5 Gold Nanorods
5.2 Synthesis of Titania Nanostructures
5.2.1 Background
5.2.2 Solvo-Thermal Synthesis of Titania Nano Crystals
5.2.3 Sol-Gel Template Synthesis of Titania Nano Tubes and Rods
5.2.4 Overview of Other Synthesis Methods
5.3 Synthesis of Zinc Oxide
5.3.1 Background
5.3.2 The Solid-Vapor Synthesis of ZnO
5.1
5.1.1 Brust Method of Synthesis of Thiol Derivatized Gold NPs by Biphasic Reduction
5.2
5.2.1 Solvo-Thermal Synthesis of Titania Nano Crystals
5.2.2 Sol-Gel Template Synthesis of Titania Nano Tubes and Rods
5.2.3 Overview of Other Synthesis Methods
5.3
5.3.1 The Solid-Vapor Synthesis of ZnO: Horizontal Tube Furnace
5.3.2 Wurtzite Structure of ZnO
References

6. Is Bionanotechnology a Panacea?
6.1 Background
6.2 Primary Concerns
6.3 Assessing Potential Risks
6.3.1 Inhalation
6.3.2 Contact/Dermal Delivery
6.3.3 Other Routes of Contact
6.3.4 Environmental Impacts of NPs and the Food Chain
6.3.5 Explosion Hazards
6.4 Lessons from the Past
6.5 Conclusion
References

7. Roadmap to Realization of Bionanotechnology
7.1 Introduction
7.2 Nano Vision: the Futuristic Goals of Bionanotech
7.3 Working toward Realization: Current Progress
7.4 Screenshot of Reality: Bionano-Unbiased/Uncensored
7.5 The Nano Mission: Roadmap to Realization of Translation Research
7.5.1 Bionano in the US
7.5.2 Bio-Nano in Japan
7.5.3 Bio-Nano in UK
7.5.4 UK–Japan Joint Initiative for Bionanotechnology
7.5.5 The EU Initiative in Bionanotech
7.5.6 Bionano in Asia

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Multifunctional Pharmaceutical Nanocarriers (Fundamental Biomedical Technologies)



by Vladimir Torchilin



About this book
Various pharmaceutical nanocarriers, such as nanospheres,nanocapsules, liposomes, micelles, cell ghosts, lipoproteins and some others are widely used for experimental (and already clinical) delivery of therapeutic and diagnostic agents. The use of nanoparticulate pharmaceutical carriers to enhance the in vivo efficiency of many drugs well established itself over the past decade both in pharmaceutical research and clinical setting. Looking into the future of the field of drug delivery, we have to think about the development of the next generation of pharmaceutical nanocarriers combining the whole variety of properties and allowing for the simultaneous performance of multiple functions. Surface modification of pharmaceutical carriers is often used to control their properties in a desirable fashion and make them to simultaneously perform several different functions. This book is all about these "futuristic" multifunctional medicines.
Key features:
-all chapters written by international leaders in the field
-offers the most recent innovations and discoveries related to nanopharmaceuticals
-detailed illustrations
-latest volume in the Fundamental Biomedical Technologies series
About the Editor:
Vladimir P. Torchilin, Ph.D., D.Sc. is a Distinguished Professor and Chair of the Department of Pharmaceutical Sciences and Director, Center for Pharmaceutical Biotechnology and Nanomedicine, Northeastern University, Boston, Mass.
Written for:
Nano-scientists and clinicians working in biology and medicine, pharmaceutical researchers, researchers interested in drug delivery and drug research, bioengineers chemists, physicists, and engineers


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Nanostructure Design: Methods and Protocols by Ehud Gazit, Ruth Nussinov







Nanostructure Design: Methods and Protocols by Ehud Gazit, Ruth Nussinov
Publisher: Humana Press | Number Of Pages: 274 | Publication Date: 2008-08-05 | ISBN-10: 1934115355 | PDF | 5 Mb

As one of the fastest growing fields of research in the 21st century, nanotechnology is sure to have an enormous impact on many aspects of our lives. Nanostructure Design: Methods and Protocols serves as a major reference for theoretical and experimental considerations in the design of biological and bio-inspired building blocks, the physical characterization of the formed structures, and the development of their technical applications. The chapters contributed by leading experts are divided into two sections, the first of which covers experimental aspects of nanostructure design and the second delves into computational methods. As a volume of the highly successful Methods in Molecular Biology™ series, this collection pulls together cutting-edge protocols, written in a step-by-step, readily reproducible format certain to guide researchers to the desired results.

Comprehensive and essential, Nanostructure Design: Methods and Protocols uses biological principles and vehicles on design to aid scientists in the great challenges still ahead.

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Nanoparticle Technology for Drug Delivery (Drugs and the Pharmaceutical Sciences)




Title: Nanoparticle Technology for Drug Delivery (Drugs and the Pharmaceutical Sciences)
ISBN: 1574448579 Author: Ram B. Gupta, Uday B. Kompella, Uday B. Kompella (Editor} Publisher: Taylor & Francis 2.8 MB PDF

Nanoparticles, products of nanotechnology, are of increasing interest to the pharmaceutical community. They can increase drug solubility, enhance bioavailability, allow tissue targeting, offer decreased side-effects, and improve therapeutic efficacy. Presenting the most pertinent and practical issues in the manufacturing and biological application of nanoparticles, this source presents state-of-the-art scientific contributions by seasoned authorities in the field.

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Nanoparticulates_As_Drug_Carriers







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Nanoparticulate Drug Delivery Systems




Nanoparticulate Drug Delivery Systems
Informa Healthcare 2007-03-30 ISBN: 0849390737 376 pages PDF 6,6 Mb

Since the advent of analytical techniques and capabilities to measure particle sizes in nanometer ranges, there has been tremendous interest in the use of nanoparticles for more efficient methods of drug delivery. This expertly written guide addresses the scientific methodologies, formulation, processing, applications, recent trends, and emerging technologies in the research of nanoparticulate drug delivery systems (NPDDS). It extensively covers applications of NPDDS, including lipid nanoparticles for dermal applications, nanocarriers for the treatment of restenosis, ocular, central nervous system, and gastrointestinal applications, and use as an adjuvant for vaccine development.



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Colloidal Nanoparticles in Biotechnology (2008)




Colloidal Nanoparticles in Biotechnology
Publisher:Wiley-Interscience Language: English ISBN:0470230525 358 pages Data: 2008 PDF 16 Mb

Description: Learn to use colloidal nanoparticles in a broad range of biotechnological applications

Discover new and emerging applications of colloidal nanoparticles. Dr. Abdelhamid Elaissari, internationally respected author and researcher, reports on and analyzes a broad range of important findings from new studies on the use of colloidal nanoparticles in biomedical, food, and environmental diagnostics and analyses. Throughout the presentation, the book uses a blend of classical tools, including optical microscopy, atomic force microscopy, microsystems, and microfluidics, to help you take full advantage of colloidal nanoparticles for your own research and applications.


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Nanoparticulates As Drug Carriers


Vladimir P. Torchilin “Nanoparticulates As Drug Carriers"
Imperial College Press 2006-09-29 ISBN: 1860946305 756 pages PDF 44,1 MB








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