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This new sixth edition of Burger's Medicinal Chemistry and Drug Discovery offers several new and unique features. For the first time, an online version of this major reference work will offer updated content from the print edition and easy access. For the first time, all volumes are structured entirely according to content and published simultaneously to provide broad coverage of medicinal chemistry and drug discovery for new or experienced medicinal chemists, biologists, pharmacologists and molecular biologists. This includes a current and global perspective of drug design, and drug development.With expanded content from 69 chapters to over 100 chapters, this sixth edition of Burger's Medicinal Chemistry and Drug Discovery includes more than 50% new material. An entire section has been dedicated to cancer research. Areas included are those at the foreground of life science including:* Proteomics* Genomics* Bioinformatics* Combinatorial Chemistry* High-Throughput Screening* Blood Substitutes* Allosteric Effectors as Potential Drugs* COX Inhibitors* Statins* High-Throughput Pharmacology* and More.The new sixth edition of Burger's Medicinal Chemistry and Drug Discovery is a Memorial Edition to Professor Alfred Burger who published this major reference work in the first edition as "Medicinal Chemistry" in two volumes in 1951. Dr. Burger's research focused on analgesics, antidepressants and chemotherapeutic agents. He is one of the few academicians to have a drug, designed and synthesized in his laboratories and brought to market. Dr. Burger's contribution to the fields of medicinal chemistry and drug discovery are well renowned and documented. He received the Louis Pasteur Medal of the Pasteur Institute and the American Chemical Society Smissman Award.
Content
VOLUME 1
Structure Based Drug-Design
History of Quantitative Structure Activity Relationships
Recent and Developing Trends in QSAR: From Data Analysis and Model Validation to Drug Design and Discovery
Molecular Modeling in Drug Design
Drug-Target Binding Forces: Advances in Force Field Approaches
Combinatorial Library Design, Molecular Similarity and Diversity Applications
Virtual Screening
Docking and Scoring Functions/Virtual Screening
Bioinformatics
Chemical Information Computing Systems in Drug Discovery
X-ray Crystallography Drug Discovery
Electron Microscopy of Biological Macromolecules
Design of Peptidomimetics
Approaches to the Rational Design of Enzyme Inhibitors
Chirality and Biological Activity
Structural Concepts in the Prediction of the Toxicity of Therapeutical Agents
Natural Products as Leads for New Pharmaceuticals
Analog Design
NMR and Drug Discovery
Mass Spectrometry and Drug Design
VOLUME 2
Combinatorial Chemistry and Multiple Parallel Synthesis
Highthroughput Screening for Lead Discovery
High Throughput Pharmacology
The Application of Recombinant DNA Technology in Medicinal Chemistry and Drug Discovery
Oligonucleotide Therapeutics
Therapeutic Agents Acting on RNA
Carbohydrate Based Therapeutics
Membrane Transport Proteins and Drug Transport
Allosteric Proteins and Drug Discovery
Receptor Targets in Drug Discovery and Development
Large Scale Synthesis
Principles of Drug Metabolism
Metabolic Considerations in Prodrug Design
Retrometabolism-Based Drug Design and Targeting
Drug Discovery: The Role of Toxicology
Drug Absorption, Distribution, and Elimination
The FDA and Regulatory Issues
Intellectual Property in Drug Discovery and Biotechnology
Nicotinic Acetylcholine Receptors
Physicochemical Characterization and Principles of Oral Dosage Form Selection
VOLUME 3
Cardiac Drugs: Antianginal, Vosodilators, Antiarrhythmic
Diuretics and Uricosuric Agents
Myocardial Infarction Agents
Endogenous Vasoactive Peptides
Hematopoietic Agents
Anticoagulatns, Antithrombotics and Hemostatics
Antihyperlipedemic Agents
Oxygen Delivery via Allosteric Effectors of Hemoglobin, Blood Substitutes, and Plasma Expanders
Sickle Cell Anemia
Iron Chelators and Therapeutic Uses
Thyroid Hormones and Thyromimetics
Male Sex Hormones, Analogs, and Antogonists
Anti-inflammatory Steroids
Female Sex Hormones, Contraceptives & Fertility Drugs
Fundamentals of Steroid Chemistry and Biochemistry
VOLUME 4
Peptide and Protein Hormones, Peptide Neurotransmitters, and Therapeutic Agents
Inhibitors of Gastric Acid Secretion
Chemokines and Cytokine Modulators
COX Inhibitors and Leukotriene Modulators
Agents Acting on Prostanoid Receptors
Retinoids
Vitamins
Life Style and Over-the-Counter Agents
Radiopaques
Microarrays and Gene Expression Profiling Applied to Drug Research
SNPs: Single Nucleotide Polymorphisms and Pharmacogenomics
Gene Therapy with Plasmid DNA
Insulin and Hypoglycemic Agents
VOLUME 5
Molecular Biology of Cancer
Synthetic DNA-targeted Chemotherapeutic Agents and Related Tumor-Activated Prodrugs
Antitumor Natural Products
Radiosensitizers and Radioprotective Agents
Synthetic Anti-angiogenic Agents
Future Strategies in Immunotherapy
Selective Toxicities
Drug Resistance in Cancer Chemotherapy
Antiviral Agents, DNA
Antiviral Agents, RNA (Viruses other than HIV), Orthopoxviruses
Rationale of Design of Anti-HIV Drugs
Organ Transplantation Drugs
Synthetic Antibacterial Agents
Lactam Antibiotics
Tetracyclines, Aminolycoside, Macrolide, and Miscellaneous Antibiotics
Antimycobacterial Agents
Antifungal Agents
Antimalarial Agents
Antiprotozoal Agents
Anthelmintic Agents
VOLUME 6
Andrenergics and Andrenergic Blocking Agents
Cholinergics
Anticholinergic Drugs
CNS Stimulants
Sedatives and Hypnotics
Anticonvulsants
Analgesics
Antidepressants
Antianxiety Agents
Antipsychotic Agents
Investigative Agents for use in Neurodegenerative Conditions
Therapeutic and Diagnostic Agents for Parkinson's Disease
Alzheimer's Disease: Search for Therapeutics
Cognition Enhancers
Drugs to Treat Eating and Body Weight Disorders
Structure Based Drug-Design
History of Quantitative Structure Activity Relationships
Recent and Developing Trends in QSAR: From Data Analysis and Model Validation to Drug Design and Discovery
Molecular Modeling in Drug Design
Drug-Target Binding Forces: Advances in Force Field Approaches
Combinatorial Library Design, Molecular Similarity and Diversity Applications
Virtual Screening
Docking and Scoring Functions/Virtual Screening
Bioinformatics
Chemical Information Computing Systems in Drug Discovery
X-ray Crystallography Drug Discovery
Electron Microscopy of Biological Macromolecules
Design of Peptidomimetics
Approaches to the Rational Design of Enzyme Inhibitors
Chirality and Biological Activity
Structural Concepts in the Prediction of the Toxicity of Therapeutical Agents
Natural Products as Leads for New Pharmaceuticals
Analog Design
NMR and Drug Discovery
Mass Spectrometry and Drug Design
VOLUME 2
Combinatorial Chemistry and Multiple Parallel Synthesis
Highthroughput Screening for Lead Discovery
High Throughput Pharmacology
The Application of Recombinant DNA Technology in Medicinal Chemistry and Drug Discovery
Oligonucleotide Therapeutics
Therapeutic Agents Acting on RNA
Carbohydrate Based Therapeutics
Membrane Transport Proteins and Drug Transport
Allosteric Proteins and Drug Discovery
Receptor Targets in Drug Discovery and Development
Large Scale Synthesis
Principles of Drug Metabolism
Metabolic Considerations in Prodrug Design
Retrometabolism-Based Drug Design and Targeting
Drug Discovery: The Role of Toxicology
Drug Absorption, Distribution, and Elimination
The FDA and Regulatory Issues
Intellectual Property in Drug Discovery and Biotechnology
Nicotinic Acetylcholine Receptors
Physicochemical Characterization and Principles of Oral Dosage Form Selection
VOLUME 3
Cardiac Drugs: Antianginal, Vosodilators, Antiarrhythmic
Diuretics and Uricosuric Agents
Myocardial Infarction Agents
Endogenous Vasoactive Peptides
Hematopoietic Agents
Anticoagulatns, Antithrombotics and Hemostatics
Antihyperlipedemic Agents
Oxygen Delivery via Allosteric Effectors of Hemoglobin, Blood Substitutes, and Plasma Expanders
Sickle Cell Anemia
Iron Chelators and Therapeutic Uses
Thyroid Hormones and Thyromimetics
Male Sex Hormones, Analogs, and Antogonists
Anti-inflammatory Steroids
Female Sex Hormones, Contraceptives & Fertility Drugs
Fundamentals of Steroid Chemistry and Biochemistry
VOLUME 4
Peptide and Protein Hormones, Peptide Neurotransmitters, and Therapeutic Agents
Inhibitors of Gastric Acid Secretion
Chemokines and Cytokine Modulators
COX Inhibitors and Leukotriene Modulators
Agents Acting on Prostanoid Receptors
Retinoids
Vitamins
Life Style and Over-the-Counter Agents
Radiopaques
Microarrays and Gene Expression Profiling Applied to Drug Research
SNPs: Single Nucleotide Polymorphisms and Pharmacogenomics
Gene Therapy with Plasmid DNA
Insulin and Hypoglycemic Agents
VOLUME 5
Molecular Biology of Cancer
Synthetic DNA-targeted Chemotherapeutic Agents and Related Tumor-Activated Prodrugs
Antitumor Natural Products
Radiosensitizers and Radioprotective Agents
Synthetic Anti-angiogenic Agents
Future Strategies in Immunotherapy
Selective Toxicities
Drug Resistance in Cancer Chemotherapy
Antiviral Agents, DNA
Antiviral Agents, RNA (Viruses other than HIV), Orthopoxviruses
Rationale of Design of Anti-HIV Drugs
Organ Transplantation Drugs
Synthetic Antibacterial Agents
Lactam Antibiotics
Tetracyclines, Aminolycoside, Macrolide, and Miscellaneous Antibiotics
Antimycobacterial Agents
Antifungal Agents
Antimalarial Agents
Antiprotozoal Agents
Anthelmintic Agents
VOLUME 6
Andrenergics and Andrenergic Blocking Agents
Cholinergics
Anticholinergic Drugs
CNS Stimulants
Sedatives and Hypnotics
Anticonvulsants
Analgesics
Antidepressants
Antianxiety Agents
Antipsychotic Agents
Investigative Agents for use in Neurodegenerative Conditions
Therapeutic and Diagnostic Agents for Parkinson's Disease
Alzheimer's Disease: Search for Therapeutics
Cognition Enhancers
Drugs to Treat Eating and Body Weight Disorders
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Vol 1 burgers medicinal chemistry.pdf
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Vol 2 burger textbook of medicinal chemistry.pdf
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Vol 3-burger medicinal chemistry.pdf
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Vol 4-burger medicinal chemistry.pdf
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Vol 5-burger medicinal chemistry.pdf
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Herbal Medicine: A Guide for Health Care Profesionals .
Pharmaceutical Press ISBN: 0853694745 2002-06-15 (2nd edition) html 296 pages 1.4 Mb RS
Pharmaceutical Press ISBN: 0853694745 2002-06-15 (2nd edition) html 296 pages 1.4 Mb RS
A general disillusionment with conventional medicines, coupled with the desire for a "natural" life style has resulted in an increasing utilization of complementary and alternative medicine (CAM) across the developed world. The global market for herbal products has grown rapidly in the past decade, yet the majority are not assessed for their quality, safety and efficacy. This completely revised and updated edition of Herbal Medicines aims to answer the questions raised for the healthcare professional by providing scientifically rigorous, impartial information on medicinal herbs. It contains: informs on quality, safety and efficacy; offersan overview of UK and European leglisation concerning herbal products; offers an account and examples ofthe scientific methods for investigating the chemical constituents of herbs and for determining their biological activities; deals with 148 herbs commonly present in herbal remedies sold by pharmacies in the UK; enables the healthcare professional to advise the public on the rational and safe use of medicines; and presents various appendices grouping together herbs with specific actions highlighting potential interactions with conventional medicine.
FieldAlign™ is a smart molecular alignment tool for modellers and medicinal chemists. Given a 3D template molecule, it can align other molecules entered in 2D to that template rapidly and in a biologically-relevant manner. The template would commonly be an active molecule (or set of molecules) in its bioactive conformation. The template molecule could be obtained from a FieldTemplater™ alignment hypothesis, a ligand extracted from the active site of a protein, docking or pharmacophore studies.
FieldAlign™ is ideal for visual inspection of alignments of actives from different series and identifying shared field features or pharmacophores, providing a qualitative indication of field SAR. FieldAlign is useful at the early stage of library design as small virtual libraries can be aligned to an active template and the chemist can select those scaffolds and monomers which together best match the active field template. FieldAlign can also be used as an aid to lead optimisation: iteratively changing molecules in FieldAlign and observing the alignments and field patterns can provide powerful insights into the direction that your chemistry should go. It is also invaluable for overlaying series of molecules prior to 3D QSAR studies where a good alignment of the molecules is critical for obtaining meaningful models.
FieldAlign™ is available as a Linux or Windows GUI program. A Linux command line version is also available which can be readily customized by expert users.
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User friendly revolutionary program that will allow you quickly and easily improve the accuracy of your clinical observations, diag- nosis and herbal prescriptions.
With a few clicks of the mouse, you can quickly and easily see more clearly the possibilities and best use of interconnected formulas, conditions, and actions.
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User friendly revolutionary program that will allow you quickly and easily improve the accuracy of your clinical observations, diag- nosis and herbal prescriptions.
With a few clicks of the mouse, you can quickly and easily see more clearly the possibilities and best use of interconnected formulas, conditions, and actions.
- Over 140 herbs and over 400 specific ailments are referenced
- Search by indication
- Unique search by multiple actions
- The program offers you the ability to add your own data.
- Preparation methods are given for each herb
- Adult dosage ranges for all appropriate preparations are given
Download
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The Art of Drug Synthesis illustrates how chemistry, biology, pharmacokinetics, and a host of other disciplines come together to produce successful medicines. The authors have compiled a collection of 21 representative categories of drugs, from which they have selected as examples many of the best-selling drugs on the market today. An introduction to each drug is provided, as well as background to the biology, pharmacology, pharmacokinetics, and drug metabolism, followed by a detailed account of the drug synthesis.
- Edited by prominent scientists working in drug discovery for Pfizer
- Meets the needs of a growing community of researchers in pharmaceutical R&D
- Provides a useful guide for practicing pharmaceutical scientists as well as a text for medicinal chemistry students
- An excellent follow-up to the very successful first book by these editors, Contemporary Drug Synthesis, but with all new therapeutic categories and drugs discussed.
A fully updated second edition of a classic, now in two volumes. It provides rapid access to information on molecular pharmacology for research scientists, clinicians and advanced students. With the A-Z format of over 2,000 entries, around 350 authors provide a complete reference to the area of molecular pharmacology. The book combines the knowledge of classic pharmacology with the more recent approach of the precise analysis of the molecular mechanisms by which drugs exert their effects. Short keyword entries define common acronyms, terms and phrases. In addition, detailed essays provide in-depth information on drugs, cellular processes, molecular targets, techniques, molecular mechanisms, and general principles.
http://rapidshare.com/files/177749248/tencyclo_molec_pharmaco2ed.zip
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William Linn, Marion Wofford, Mary Elizabeth O'Keefe, L. Michael Posey "Pharmacotherapy in Primary Care"
McGraw-Hill Medical 2008-09-21 ISBN: 0071456120 544 pages PDF 3,6 MB
McGraw-Hill Medical 2008-09-21 ISBN: 0071456120 544 pages PDF 3,6 MB
A complete single-source guide to drug therapeutics for primary care
Pharmacotherapy in Primary Care gives you a uniquely balanced, all-inclusive look at drug therapies for all the conditions commonly seen in primary care and clinical pharmacy -- from cardiovascular to nutritional disorders.
The book's diverse authorship -- comprising both physicians and pharmacists -- ensures that content is delivered in the most complete, relevant, and impartial way possible. Ideal for use at the point of care, this handy resource is conveniently organized by disorder and utilizes a standard template for therapeutic decision-making.
FEATURES.
A high-yield, systematic review of the clinical literature that informs pharmacotherapy interventions.
Specific recommendations that optimize drug therapy for each disorder covered in the book.
Helpful treatment algorithms to speed clinical decision-making.
Evidence-based summaries that present the book's insights within the highly practical context of evidence-based medicine .
Important emphasis on identifying the variables that go into initial drug therapy decisions--plus key issues related to long-term monitoring, contingency planning, and referral
First published in 1959, the "Big Red Book," as it's come to be known, has gone the extra mile for pharmacists and healthcare professionals seeking answers to the most detailed questions. It provides more extensive evidence-based data than any other drug reference. AHFS DI is the only reference free from the influence of manufacturers, insurers, regulators, and other special interests, giving you an unbiased source of drug information.
if messages about scripts error bother you try this:first define the drug you want, than click on + to open all subfolder which lie in the medicine name direction, than click on + near folder Document Body Date - and choose AFHS Drug InformationB(2008) - if you will work in such way you will recieve only one message about error.
Worldwide, there are varying Codes of Practice/Conduct for the pharmaceutical industry that ensure the industry self-regulates to promote the appropriate use of medicines by operating in a professional, ethical and transparent manner and ensuring high standards.The aim of this book is to aid the understanding of the many pharmaceutical Codes of Practice/Conduct throughout the world. It contains an overview of the guidelines for the promotion of pharmaceutical products in all geographical areas.Each section includes a "general overview" providing a discussion on that particular Code of Practice and differences/similarities with other countries.
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Written by an internationally renowned authority in the field, this is the most complete dictionary devoted specifically to the terms currently used in pharmacoepidemiology. The use of
clear and consistent terminology in science has never been more important, and this dictionary, which has been translated from the third edition of a French original, has been reworked to include suggestions made by pharmacoepidemiologists currently using existing versions. It contains revised definitions for nearly all established terms in addition to comprehensive descriptions of new terms and is well illustrated with practical examples. This outstandingly high-quality dictionary will be essential for all those whose work is within or touches upon this field: regulatory authorities, pharmaceutical physicians, lawyers, pharmacists, researchers, evaluators and students.
Download Link:
http://rapidshare.com/files/128792402/Dict_pharmacoepid.zip
clear and consistent terminology in science has never been more important, and this dictionary, which has been translated from the third edition of a French original, has been reworked to include suggestions made by pharmacoepidemiologists currently using existing versions. It contains revised definitions for nearly all established terms in addition to comprehensive descriptions of new terms and is well illustrated with practical examples. This outstandingly high-quality dictionary will be essential for all those whose work is within or touches upon this field: regulatory authorities, pharmaceutical physicians, lawyers, pharmacists, researchers, evaluators and students.
Download Link:
http://rapidshare.com/files/128792402/Dict_pharmacoepid.zip
The Third Edition of this successful book has been revised and updated to include the latest advances in the field. It incorporates new topics such as prescription event monitoring, general practice research database, and drug utilization review.
- Provides an American and European perspective.
- The authors are renowned in the field.
http://rapidshare.com/files/13723635/PharmacoEpidemiology__3e_2000_.rar
password:econiches
Drug-like Properties: Concepts, Structure Design and Methods
Publisher:Academic Press Pages:552 2008-02-01 ISBN:0123695201 PDF 5 MB
Of the thousands of novel compounds that a drug discovery project team invents and that bind to the therapeutic target, typically only a fraction of these have sufficient ADME/Tox properties to become a drug product. Understanding ADME/Tox is critical for all drug researchers, owing to its increasing importance in advancing high quality candidates to clinical studies and the processes of drug discovery. If the properties are weak, the candidate will have a high risk of failure or be less desirable as a drug product. This book is a tool and resource for scientists engaged in, or preparing for, the selection and optimization process.
The authors describe how properties affect in vivo pharmacological activity and impact in vitro assays. Individual drug-like properties are discussed from a practical point of view, such as solubility, permeability and metabolic stability, with regard to fundamental understanding, applications of property data in drug discovery and examples of structural modifications that have achieved improved property performance. The authors also review various methods for the screening (high throughput), diagnosis (medium throughput) and in-depth (low throughput) analysis of drug properties.
* Serves as an essential working handbook aimed at scientists and students in medicinal chemistry
* Provides practical, step-by-step guidance on property fundamentals, effects, structure-property relationships, and structure modification strategies
* Discusses improvements in pharmacokinetics from a practical chemist's standpoint
Pharmacology for the Health Care Professions
Publisher:Wiley Pages:376 2008-12-10 ISBN:0470510188 PDF 1.2 MB
Pharmacology for the Health Care Professions is an accessible introduction to the pharmacology necessary for health care professionals training to be non-medical prescribers looking for an overview of the subject. The book covers the pharmacology necessary for accredited training programmes in non-medical prescribing and certification in access and supply of prescription-only medicines and will be useful as an ongoing reference for future use in practice.
Opening with a general introduction to pharmacology as a science, the book goes on to explain what is meant by drugs and medicines and why pharmacology should be of relevance to health care professionals. The reader is presented with general principles of pharmacology followed by systemic pharmacology that covers the actions of important groups of drugs in common use to treat diseases and conditions of the cardiovascular, respiratory, endocrine, musculoskeletal, skin and central nervous systems. The physiology and pathophysiology relevant to the understanding of how these drugs work is included.
Finally the book explores the law in relation to the sale, supply, administration and prescription of drugs and explains what is meant by non-medical prescribing. All aspects of non-medical prescribing are considered including the use of exemptions to the Medicines Act, patient group directions, supplementary prescribing and the development of independent prescribing for nurses and pharmacists.
Pharmacology is explained in simple, easy to understand terms and the book avoids any unnecessary chemistry where possible. Case studies that are of particular relevance to health care professionals are used throughout to illustrate the importance of the pharmacology major body systems and pathologies and the potential problems of adverse drug reactions and drug-drug interactions.
Bob Flaws “70 Essential Chinese Herbal Formulas"
Blue Poppy Press 1994-10-01 ISBN: 0936185597 250 pages Html 2,3 MB
Blue Poppy Press 1994-10-01 ISBN: 0936185597 250 pages Html 2,3 MB
At TCM colleges in China, undergraduates learn a basic repertoire of between 50 and 100 herbal formulas. This includes one or two formulas from each of 21 major categories. By learning to modify this core group of formulas with additions and subtractions, one will have a basic repertoire of formulas for most clinical occasions. This book is not meant to replace or compete with Bensky & Barolet's Chinese Herbal Medicine: Formulas & Strategies. It is meant as an outline for prioritized study and use by under-graduates and new practitioners
McGraw-Hill's I.V. Drug Handbook by Patricia Dwyer Schull
Publisher: McGraw-Hill Professional ISBN: 0071548637 2008 PDF 734 pages 9.8 Mb rared
Product Description:
Administer I.V. medications knowledgeably, safely and confidently
Because there's no room for error, turn to McGraw-Hill's I.V. Drug Handbook. Featuring a strong focus on patient safety, administering and monitoring I.V. drugs, the Handbook delivers concise, practical guidance to help you carry out one of the most difficult tasks you face. Written by and for practicing nurses and pharmacists, the Handbook is reliable, comprehensive, and easy-to-use.
Everything you need for safe, successful I.V. drug administration:
* All-inclusive coverage of over 350 parenteral drugs with the latest warnings from the FDA
* Includes antibiotics, insulin, pain medications, emergency drugs -- and more coverage of chemotherapeutic agents with more supportive therapies than you'll find in any other text
* Provides the most comprehensive, specific, evidence-based guidelines on administering high-alert and hazardous drugs available anywhere
* Each drug monograph includes administration guidelines, covering preparation, dilution & compatibility, infusion rates, admixtures, supportive therapies and monitoring.
* Features a 32 page full-color patient safety insert describing measures for ensuring safe drug administration, including 6 pagea on inserting an I.V. catheter
* Uses distinctive icons to call your attention to “clinical alerts,” “life-threatening reactions,” “high-alert”, “hazardous” drugs, and more
John Mann "Life Saving Drugs: The Elusive Magic Bullet"
Published by Royal Society of Chemistry November 2004 ISBN : 0854046348 PDF Format, 234 pages English 15.2 MB
Published by Royal Society of Chemistry November 2004 ISBN : 0854046348 PDF Format, 234 pages English 15.2 MB
In 1900 only a handful of drugs (morphine, quinine, aspirin etc) had genuine efficacy and recovery from infections was haphazard. Now there are literally thousands of drugs and life-threatening infections have been either overcome or much diminished.
Life-saving Drugs: the Elusive Magic Bullet describes the discovery and development of antibacterial, anti-viral and anti-cancer drugs. The book highlights the colourful characters behind the inventions and the huge improvements in quality of life and life-expectancy that these drugs have produced.
Emphasis is given to the new drugs that have emerged as a result of knowledge of the human genome, and the ways in which the newer drugs are being designed to tackle disease, particularly cancer, at the genetic level. Chemical structures are provided for all of the key drugs and the book is well illustrated.
Life-saving Drugs: the Elusive Magic Bullet can be read as a history of drug development during the past 100 years by those with only a passing knowledge of chemistry. For anyone entering the medical profession, pharmacy, or nursing, it will provide a superb basic knowledge of all drugs they are ever likely to meet, including their modes of action. For the chemist or medicinal chemist, it will provide the fundamental knowledge of life-saving drugs that they all should know. And for the non-scientist who wants to know about 'super-bugs', SARS, Ebola, and all of the wonderful advances in treating cancer, it is illuminating and easy to read.
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Drugs Compromising Male Sexual Health by Walter Krause
Publisher: Springer 2008-01 | 702 Pages | ISBN: 3540698590 | PDF | 2.8 MB
Publisher: Springer 2008-01 | 702 Pages | ISBN: 3540698590 | PDF | 2.8 MB
This concise drug guide lists 500 substances, such as pharmaceutical drugs, lifestyle drugs, and environmental toxicants, that show documented untoward effects on the male sexual organs and their functions. All substances are listed in user-friendly alphabetical order with a uniform structure throughout the book. Each listing includes evidence-based information with up-to-date references and all studies mentioned are evaluated and categorized according to study and sample types.
This unique compendium provides more detailed information on each drug than any other standard pharmacology title. Knowledge of the relevance of undesirable drug effects will enable the physician working in the fields of andrology and reproductive medicine to decide whether there is a relationship between a disturbance of male sexual function and a drugs adverse side effects. An electronic CD-ROM accompanies the book.
Rick Ng " Drugs: From Discovery to Approval, 2 Ed."
Wiley-Blackwell 2008-12-03 ISBN: 047019510X 466 pages PDF 4,9 MB
Wiley-Blackwell 2008-12-03 ISBN: 047019510X 466 pages PDF 4,9 MB
The new edition of this best-selling book continues to offer a user-friendly, step-by-step introduction to all the key processes involved in bringing a drug to the market, including the performance of pre-clinical studies, the conduct of human clinical trials, regulatory controls, and even the manufacturing processes for pharmaceutical products. Concise and easy to read, the book quickly introduces basic concepts, then moves on to discuss target selection and the drug discovery process for both small and large molecular drugs. The new edition features many key enhancements, including Key Points, Chapter Summary, and Review Questions in each chapter, Answers to Review Questions provided in a book-end appendix, and one or two carefully selected "mini" case studies in each chapter.
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